No, I don't think it was malware - I spent a fair amount of time looking, after rebooting into safe mode.
How about restoring to Windows Update's June restore point? No dice.
So, in 100 days, Vista got crufty, and it's being re-imaged right now.
Here at home is a different story:
ted@Ubuntu:~$ uptimeI updated drivers last month, so my uptime is "only" 3 weeks and change.
19:35:50 up 24 days, 35 min, 2 users, load average: 0.20, 0.23, 0.23
Rock solid, no spyware. The way I like it.